Biotalys Reports Full-Year 2025 Financial Results and Business Highlights

Annual Results & Strategic Outlook

Biotalys Announces 2025 Financial Results and Strategic Pivot Toward Commercial Readiness

EPA Approval of EVOCA™ Validates AGROBODY™ Platform for Sustainable Crop Protection

Year-End Cash

€8.0 Million

Financial Runway

End of May 2026

Regulatory Status

U.S. EPA Approved

Biotalys (Euronext: BTLS) has announced its consolidated financial results for 2025, highlighting a major value inflection point with the U.S. EPA approval of EVOCA™, its first protein-based biocontrol. The company is currently implementing a strategic refocus to concentrate resources on high-priority commercial programs, aiming to materially reduce its cash burn until the end of 2028.

Strategic Refocus and Operational Streamlining

Following a post-period decision in early February 2026, Biotalys is proceeding with a streamlined operational model:

  • Suspension of early-stage activities to reduce operating expenses while safeguarding the technology platform.
  • Prioritization of lead biofungicide assets, EVOCA™ and BioFun-6, in high-value markets.
  • Opening research programs BioFun-4 and BioFun-8 for R&D collaboration with third parties.

Pipeline and Regulatory Progress

The company’s product pipeline achieved several critical milestones throughout 2025 and early 2026:

  • EVOCA™: Earned U.S. EPA approval in December 2025 and Florida state registration in April 2026. In Europe, the Dutch regulator (CTGB) has recommended approval throughout the EU.
  • BioFun-6: Field trials demonstrated increased potency, matching EVOCA’s performance at significantly lower dosage rates.
  • BioIns-2: Advanced in collaboration with Syngenta, reaching a first research milestone in April 2026.
  • Intellectual Property: Expanded patent protection for EVOCA™ in China and Brazil, and obtained a U.S. patent for BioFun-6 active ingredients.

Financial and Partnership Highlights

Biotalys forged key partnerships to accelerate production and expand into post-harvest markets:

  • 21st.BIO Partnership: Collaborating with the Danish precision fermentation leader to scale production at commercially competitive costs.
  • AgroFresh Alliance: Developing sustainable solutions to reduce global food waste from fungal decay in post-harvest produce.
  • Financing: While the current runway extends to May 2026, negotiations with investors regarding further financing options are well-advanced.

Leadership Transitions

The company has streamlined its leadership to guide this commercial phase:

  • Carlo Boutton: Appointed as CEO ad interim in March 2026.
  • Luc Van fraeyenhoven: Appointed as CFO in May 2025 to provide cost-conscious financial leadership.
  • Audit Committee: Patrik Haesen appointed as Chair of the Audit Committee.
“Sharpening our focus on advanced biofungicide programs to implement a streamlined model designed to reduce cash burn.”

Biotalys – Agricultural Technology

Annual Report 2025 | Gent, Belgium | biotalys.com

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