Summary: NewLeaf Symbiotics® has expanded the label for its EPA-registered bioinsecticide, TS201, making it available as a planter-box solution for corn, soybeans, cotton, and rice in 2026. Powered by proprietary PPFM technology, TS201 triggers induced systemic resistance (ISR) to proactively defend plants against various yield-robbing insects and nematodes. Backed by extensive field data, TS201 provides growers with a powerful new mode of action to increase plant vigor and maximize return on investment.
Data-backed PPFM technology provides another tool in fight against yield robbing insects
St. Louis — February 4, 2026
Inside every plant is the ability to defend itself. NewLeaf Symbiotics® brings that ability to the forefront with its EPA-registered bioinsecticide technology TS201, now available on corn, soy, cotton and rice. Setting your plants up to defend themselves against insect pressure, the revolutionary technology from NewLeaf Symbiotics, the pioneer and global leader in PPFMs (Pink-Pigmented Facultative Methylotrophs) provides another tool and an additional mode of action to growers’ pest management toolbox.
“TS201 uses a mode of action called induced systemic resistance (ISR) to deliver added defenses in-season,” says Aaron Kelley, Chief Commercial Officer for NewLeaf Symbiotics. “ISR primes the plant’s natural defenses against a number of pests, making it quicker to react to known threats in season. You’re not waiting on your scout to start to fight against the threat, your plant is the first line of defense.”
That type of reaction can translate to added bushels at the end of the season. In research trials, TS201 demonstrated consistent performance against juvenile and adult insects across insect orders and plant species.
When paired with NewLeaf’s crop-specific biostimulants for early season enhanced nutrient uptake increasing vigor, that ROI grows. For example, TS201 returned an 8.7 bu/A advantage in corn for 10+acre field trials conducted on 91 locations from 2023-2025.1
- Corn: Corn Rootworm, Fall Armyworm, Root Knot Nematode, Wireworm
- Soybeans: Root Knot Nematode, Soybean Looper, Stink Bug
- Cotton: Root Knot Nematode, Thrips
- Rice: Water Weevil
“At NewLeaf, we don’t commercially release a new technology to growers unless it has been extensively tested – that includes lab, greenhouse, small plots and large plot field trials,” adds Kelley. “Our customers have come to expect gold standard biologicals that are science-led, performance-driven and backed by data. It’s part of the system that makes NewLeaf different. This expansion for TS201 is the latest vetted technology demonstrating results from NewLeaf.”
NewLeaf used its science-led, performance-driven and data-backed approach to launch TS201 in 2024 as a corn bioinsecticide effective at repelling corn rootworm larvae. TS201 has been its most successful technology to date and recommended to be paired with NewLeaf’s corn-specific biostimulant for added plant vigor.
TS201 is approved as a planter-box solution for 2026 planting in corn, soybeans, cotton and rice. To learn more about TS201 and other NewLeaf technologies, visit newleafsym.com.
About NewLeaf Symbiotics
NewLeaf Symbiotics is a biological technology provider known as the pioneer and global leader of Pink-Pigmented Facultative Methylotrophs (PPFMs) and methanotrophs, a closely related microbe. NewLeaf has nine technologies on ten crops developed over the last decade and has a pipeline backed by more than 250 patents focused on sustainable and yield-based outcomes in crop production. Ranging from row crops to specialty operations, NewLeaf is dedicated to a science-led, performance-driven and data-backed approach that delivers results to its partners and the growers they support.
1Yield advantage calculated from win performance when TS201 was paired with Terrasym® 450 biostimulant.
Always read and follow label directions. Not all products are registered for use in all states and may be subject to use restrictions. Performance, results and yield may vary, from location to location and from year to year, as local growing, soil and environment conditions may vary. Growers should evaluate data from multiple locations and years whenever possible and should consider the impacts of these conditions on their growing environment.

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