BIOSPHÆRE Selected Under France 2030 –Regionalized i-Demo Program with Support fromthe Sud Region and Hauts-de-France Region

Public-Private R&D Mobilization

BIOSPHÆRE Selected Under France 2030 – Regionalized i-Demo Program with Support from the Sud Region and Hauts-de-France Region

€3 Million Consortium Deploys Interregional Public Funding to Build Enzyme and Lipopeptide Crop Controls

In a major federal activation to accelerate clean crop-residue strategies across the Mediterranean corridor, BIOSPHÆRE Selected Under France 2030 – Regionalized i-Demo Program with Support from the Sud Region and Hauts-de-France Region. Announced on June 24, 2026, the 36-month program is backed by €1.5 million in public co-funding to total a €3 million consortium framework. Coordinated by biotech pioneer Gene&GreenTK, the alliance unites specialized ag-input producer Lipofabrik (Eléphant Vert Group), national research agency INRAE, and experimental testing hub Enigma. This elite consortium is engineering an integrated, low-risk defensive platform that merges antimicrobial enzymes and industrial lipopeptides to shield strategic tomato crop clusters against invasive insect pests and deep-seated bacterial or fungal pathogens.

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MARSEILLE, FRANCE — June 24, 2026 — A French consortium of excellence, bringing together Gene&GreenTK, Lipofabrik (Eléphant Vert Group), INRAE, and Enigma, has joined forces to develop a new generation of sustainable biosolutions for tomato crop protection.

Key Program Figures

Program Frame: France 2030 – Regionalized i-Demo Program (Interregional Partnership between Sud Region and Hauts-de-France Region).
Project Timeline: 36 Months | Duration spanning January 2026 through December 2028.
Financial Structure: €3 Million Total Budget | Supported by €1.5 Million in Public Investment.
Management: 4 Specialist Partners | Domestically coordinated via Gene&GreenTK.

Background & Operational Objectives

In response to intense environmental and regulatory challenges associated with reducing the use of conventional plant protection products, BIOSPHÆRE aims to develop and evaluate new alternative biological substances capable of providing effective and sustainable crop protection. The project will primarily focus on tomato crops, a strategic sector for the Sud Region due to its economic importance, strong national demand, and the increasing phytosanitary challenges faced by the greenhouse and open-field industry. The objective is to secure crop yields against destructive insect vectors alongside heavy bacterial and fungal diseases.

“BIOSPHÆRE embodies a new generation of biological solutions capable of addressing the agricultural, environmental, and industrial challenges of tomorrow.” — David Daudé, CEO of Gene&GreenTK.

“BIOSPHÆRE goes beyond delivering a product. It provides practical solutions to help tomato growers manage uncertainty and operate their crops in a more stable and reliable way.” — Luc Maertens, Chief Strategy & Portfolio Officer at Lipofabrik – Eléphant Vert Group.

Core Pipeline Technologies

The solutions developed within the BIOSPHÆRE project will be based on innovative biological approaches combining:

Antimicrobial enzymes;
Biocontrol lipopeptides;
Biocontrol microorganisms;
Natural antifungal substances.

The program moves from the production and formulation of active substances to advanced field trials under real growing conditions, explicitly testing industrial scale-up viability, economic unit parameters, and strict EU regulatory compliance pathways to accelerate agroecological transitions.

Consortium Partner Matrix

Gene&GreenTK (Marseille) — Coordinator: An innovative startup specializing in the development of antimicrobial enzymes, driving optimization and candidate extraction pipelines.
Lipofabrik – Eléphant Vert Group (Lesquin): A specialized biomanufacturer scaling lipopeptides and microbial derivatives, leading product formulation and advanced industrial scaling.
INRAE – Provence-Alpes-Côte d’Azur Centre (Avignon): The leading national research institute heading scientific pathology evaluations and tracking plant-pathogen rhizosphere interactions.
Enigma (Beaumes-de-Venise): A premier testing laboratory with 20 years of experience in phytopharmaceutical validation, executing crop trials on insect pests under real field conditions.

Strategic Market Context

The deployment of state-backed interregional capital into advanced enzyme and lipopeptide R&D reflects a macro trend where national governments co-invest to de-risk biological discovery for critical food security segments. As regulatory ceilings restrict traditional synthetics, agricultural blocks are building domestic manufacturing chains. This infrastructure expansion runs parallel to major milestone clearances across the European biocontrol landscape, such as Amoéba securing a landmark 15-year EU marketing clearance for AXPERA to commercialize unique microbial lysates, and Certis Belchim and Greenhas Group entering a joint venture to co-develop biostimulants, cementing the complete integration of molecular crop biology into mainstream distribution networks.

“Merging public structural investment with private biotechnology to construct resilient, residue-free crop systems for regional agriculture.”

Gene&GreenTK S.A.S. — BIOSPHÆRE Central Registry

Marseille, France | France 2030 Innovation Briefing | June 2026 | gene-greentk.com