On July 24, 2025, the Government of Argentina made a decisive move to modernize its agricultural input landscape by publishing Resolution 128/2025 in the Official Gazette. This new regulation repeals the earlier Resolution 41/2021, and introduces a refreshed, streamlined, and science-driven regulatory framework for bioinputs. The change reflects Argentina’s broader strategic alignment with global sustainability trends and its ambition to lead Latin America’s emerging bioeconomy revolution.

What Are Bioinputs?

The new resolution defines bioinputs as biological products made from microorganisms, macroorganisms, extracts, or derived bioactive compounds. These products can serve diverse functions such as:

• Biofertilizers
• Phytostimulants
• Phytoregulators
• Biocontrollers
• Phytosanitary agents
• Bioremediators and biotransformers
• Bioinputs for energy generation

This broad categorization aims to capture the full scope of biological innovations applicable to agriculture, waste remediation, plant health, and soil regeneration.

Why the Reform Was Needed

Resolution 41/2021 was seen as a necessary first step, but it lacked clarity in definitions, processes, and implementation pathways. With biotechnology and sustainable inputs gaining commercial momentum globally, Argentina needed a more agile and integrated framework to regulate, support, and promote this new generation of agricultural technologies.

Resolution 128/2025 is designed not just to regulate, but to catalyze innovation, incentivize product development, and provide scientific and institutional support to stakeholders working on bio-based solutions.

Introduction of CABUA: Governance with Scientific and Sectoral Inputs

The resolution re-establishes the Advisory Commission on Bioinputs for Agricultural Use (CABUA) under the Ministry of Economy. This committee will now operate within the Innovation and Biotechnology Coordination Office, which falls under the Ministry’s National Directorate of Bioeconomy.

CABUA’s Key Responsibilities Include:

• Providing technical and scientific advice to the regulatory authority
• Evaluating product submissions for the “Argentine Bioproduct” Seal
• Recommending regulatory updates in response to emerging trends and technologies
• Contributing to policy, plan, and project design in support of bioinput commercialization

Inclusivity and Participation: CABUA is inclusive in its composition, bringing together representatives from public, private, academic, and civil society sectors. Members serve on an honorary basis, ensuring transparency and fiscal responsibility, as no additional costs are imposed on the state.

The “Argentine Bioproduct” Seal: A Quality and Origin Mark

One of the more strategic features of the new resolution is the formalization of the “Argentine Bioproduct” seal. This label, issued after technical validation by CABUA, serves as both a trustmark for farmers and consumers and a market differentiation tool for developers. The seal confirms a product’s biological origin, performance, and compliance with regulatory standards, enabling local producers to gain competitive visibility in national and international markets.

Promoting a Bioeconomy Mindset

This move comes amid growing global demand for eco-friendly and sustainable agricultural practices. Argentina, with its vast agricultural land and established research institutions, is positioning itself as a regional leader in biological solutions and green technologies. Resolution 128/2025 provides a legal and institutional foundation for integrating biotechnology, environmental sustainability, and agriculture.

It also encourages public-private-academic collaboration, aiming to reduce chemical dependency in farming, improve soil and plant health, and support climate resilience goals under Argentina’s broader sustainability commitments.

Simplification Without Sacrificing Oversight

The revised regulation introduces clearer terminology, streamlined procedures, and flexible implementation tools. At the same time, it preserves rigorous oversight by requiring all stakeholders to align with national innovation standards and bioeconomic goals. By clarifying what constitutes a bioinput and by anchoring the evaluation process within CABUA, the resolution reduces regulatory ambiguity while safeguarding quality assurance.

Conclusion: A Future-Facing Agricultural Policy

Resolution 128/2025 represents more than a policy upgrade—it is a step toward redefining agricultural development through science and sustainability. Argentina is creating fertile ground for bioinnovation to flourish, backed by a governance model that is participatory, evidence-driven, and attuned to global trends.

For startups, scientists, cooperatives, and agri-tech entrepreneurs, this change signals opportunity. For farmers and ecosystems, it offers the promise of a healthier, less chemically intensive future. And for policy watchers across Latin America, it stands as a model for how progressive regulation can enable real impact on the ground.